Kalyn's Kitchen

Horseradish Meatloaf with Sour Cream-Horseradish Sauce

Horseradish Meatloaf with Sour Cream-Horseradish Sauce is perfect to make on the weekend and enjoy during the week, and this can be low-carb!

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Horseradish Meatloaf with Sour Cream-Horseradish Sauce finished meatloaf with sauce on plate

I think Horseradish Meatloaf with Sour Cream-Horseradish Sauce is really something special in the meatloaf world, with added flavor from caramelized onions, garlic, horseradish, Worcestershire sauce, and a touch of sour cream mixed into the meat before it’s cooked, and a tasty sauce of sour cream, mayo, and horseradish. And if you use my newly-preferred Flaxseed Meal to find the meatloaf together, this can easily be low-carb and gluten-free!

But this is not quick and easy meatloaf. This is meatloaf to make on Sunday afternoon when you have time to gently caramelize the onions, mix the ingredients together, mix the sauce, and then enjoy leftover meatloaf for lunch all week.

I originally made this tasty meatloaf with a small amount of breadcrumbs, so it wasn’t gluten-free and did have a few carbs. But through the years I’ve started to love Flaxseed Meal (affiliate link) as a binder in meatloaf and meatballs, and the flax seeds have so much fiber that the net carbs are really low. Take your choice on using that for less carbs, or make the original version with breadcrumbs if you don’t mind a few carbs and don’t care if it’s gluten-free.

What ingredients do you need for this recipe?

  • onions
  • olive oil
  • Minced Garlic (affiliate link)
  • dried thyme
  • eggs
  • sour cream
  • cream-style Prepared Horseradish (affiliate link)
  • Worcestershire sauce
  • ground beef
  • Flaxseed Meal (affiliate link)
  • salt and fresh ground black pepper
  • mayo

Want an Easier Meatloaf Recipe?

If you’re not up for this much work for meatloaf, you may want to make what my sister Pam dubbed Kalyn’s Best Meatloaf, a version I made for years with canned mushroom soup and onion soup mix. That was good meatloaf too, back in the day when I used to cook with those kinds of ingredients, but if you have more time, my dad gave the Horseradish Meatloaf two thumbs up!

Horseradish Meatloaf with Sour Cream-Horseradish Sauce process shots collage

How to make this recipe:

(Scroll down for complete recipe with nutritional information.)

  1. Dice two medium onions into fairly small pieces, then heat olive oil and start to cook the onions. Let onions cook at low heat stirring every few minutes until onions are nicely browned and caramelized, about 30 minutes.
  2. Don’t rush the browning step and be sure onions don’t burn or they will be bitter.
  3. After onions cook for 15 minutes, start preheating oven to 375F/190C.
  4. Add Minced Garlic (affiliate link) and dried thyme to the onions and cook about 2 minutes more.
  5. Mix together eggs, sour cream, Prepared Horseradish (affiliate link), and Worcestershire sauce.
  6. Put ground beef into a bowl and let it come to room temperature. When onions are done, add Flaxseed Meal (affiliate link) and onion-garlic mixture to the meat and season with salt and fresh ground black pepper. 
  7. Add egg/sour cream/horseradish/Worcestershire sauce mixture to meat. 
  8. Use your hands to gently combine until all the ingredients are well-mixed.
  9. I bought this broiler pan at a thrift store years ago, and love to use it to cook meatloaf. The slits let the fat drip down into the lower pan, so the meatloaf gets nice and crispy on the outside.
  10. Form the meat mixture into a loaf and place on top of the broiler pan (or roasting pan of your choice.) I like to make criss-cross slits on top of the meatloaf, but it’s completely optional!
  11. Bake meatloaf at 375F/190C for about 75 minutes, or until meat reaches 55-160F on an  Instant Read Meat Thermometer (affiliate link). I let mine go a bit too long but the sour cream still kept it moist!
  12. Let meatloaf cool for 10-15 minutes before cutting; then serve with Sour Cream-Horseradish Sauce if desired.

Horseradish Meatloaf with Sour Cream-Horseradish Sauce thumbnail image of finished meatloaf

Make It a Low-Carb Meal:

Horseradish Meatloaf with Caramelized Onions and Sour Cream Horseradish Sauce would be great with Pureed Cauliflower with Garlic, Parmesan, and Goat Cheese or Twice Baked Cauliflower and Kale and Red Cabbage Slaw for a low-carb meal.

More Tasty Recipes for Meatloaf:

Grain-Free Beef and Sausage Meatloaf 
Meatloaf Balls with Italian Sausage, Ground Beef, and Peppers 
Turkey Pesto Meatloaf 

Horseradish Meatloaf with Sour Cream-Horseradish Sauce finished meatloaf with sauce on plate

Horseradish Meatloaf with Sour Cream-Horseradish Sauce

Yield 8 servings
Prep Time 1 hour
Cook Time 1 hour 15 minutes
Total Time 2 hours 15 minutes

Make this Horseradish Meatloaf with Sour Cream-Horseradish Sauce on the weekend and enjoy leftovers during the week!

Ingredients

Ingredients

  • 2 medium onions, diced into small pieces
  • 1 T tsp. olive oil (more or less, depending on your pan)
  • 1 T finely minced garlic
  • 1 tsp. dried thyme
  • 2 eggs, beaten
  • 1/4 cup sour cream
  • 3 T cream-style horseradish (not horseradish sauce)
  • 1 T Worcestershire sauce
  • 2 lbs. ground beef
  • 1/2 cup Flaxseed Meal (see notes)
  • salt and fresh ground black pepper to taste

Sauce Ingredients

  • 1/4 cup sour cream
  • 2 T mayo
  • 2 T cream-style horseradish

Instructions

  1. Dice two medium onions into fairly small pieces, then heat olive oil in a large heavy pan and start to cook the onions over low heat.
  2. Let onions cook at low heat stirring every few minutes until onions are nicely browned and caramelized, about 30 minutes.
  3. Don’t rush this step and be sure onions don’t burn or they will be bitter.
  4. After onions cook for 15 minutes, start preheating oven to 375F/190C.
  5. Add minced garlic and dried thyme to the onions and cook about 2 minutes more.
  6. Mix together eggs, sour cream, horseradish, and Worcestershire sauce.
  7. Put ground beef into a bowl and let it come to room temperature.
  8. When onions are done, add Flaxseed Meal (affiliate link) and onion-garlic mixture to the meat and season with salt and fresh ground black pepper.
  9. Add egg/sour cream/horseradish/Worcestershire sauce mixture to meat. (Adding this on top of the onions will help cool them.)
  10. Use your hands to gently combine until all the ingredients are well-mixed.
  11. Form the meat mixture into a loaf and place on top of the broiler pan (or roasting pan of your choice.)
  12. I like to make criss-cross slits on top of the meatloaf, but it's completely optional!
  13. Bake meatloaf at 375F/190C for about 75 minutes, or until meat reaches 55-160F on an  Instant Read Meat Thermometer (affiliate link).
  14. Let meatloaf cool for 10-15 minutes before cutting; then serve with Sour Cream-Horseradish Sauce if desired.

Notes

I loved this with Flaxseed Meal (affiliate link) for a low-carb version, but make it with breadcrumbs if you prefer.

Recipe adapted by Kalyn from notes copied years ago from a friend’s cookbook, but unfortunately the notes didn’t include the name of the book.

Nutrition Information:

Yield:

8

Serving Size:

1

Amount Per Serving: Calories: 475Total Fat: 34gSaturated Fat: 12gTrans Fat: 1gUnsaturated Fat: 18gCholesterol: 168mgSodium: 252mgCarbohydrates: 6gFiber: 2gSugar: 2gProtein: 34g

Nutrition information is automatically calculated by the Recipe Plug-In I am using. I am not a nutritionist and cannot guarantee 100% accuracy, since many variables affect those calculations.

If you make this recipe I'd love to hear how it turns out. Leave a star rating or share on social media with the hashtag #KALYNSKITCHEN, thanks!

Low-Carb Diet / Low-Glycemic Diet / South Beach Diet Suggestions:
When made with Flaxseed Meal (affiliate link), this Horseradish Meatloaf with Caramelized Onions and Sour Cream-Horseradish Sauce is a pretty low-carb and low-glycemic recipe, suitable for low-carb eating plans. If it’s made with ground beef with 10% fat or less, the meatloaf is great for phase 2 or 3 of the original South Beach Diet. 

Find More Recipes Like This One:
Use Oven Dinners to find more recipes like this one. Use the Recipes by Diet Type photo index pages to find more recipes suitable for a specific eating plan. You might also like to Follow Kalyn’s Kitchen on Pinterest to see all the good recipes I’m sharing there.

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    53 Comments on “Horseradish Meatloaf with Sour Cream-Horseradish Sauce”

  1. I am late to this party, but this was just perfect. So different from the normal ketchup yuckyness. I will make this again, absolutely!

  2. Lindi, so glad you liked it. I know what you mean about the breadcrumbs, but I'm not sure it would work without them.

  3. I've been married 36 years and my husband and I have never found a meatloaf recipe we agreed upon. He normally likes lots of egg and catsup. I prefer less egg and no catsup. We both like horseradish, though, so when I saw this, I thought I'd try it. Well, I still like my mom's the best, but this was good. And my husband really liked it. The big surprise was my granddaughter, who lives with us, thought it was absolutely delicious! So, I guess it is the new go-to. I would like to try leaving out the wheat crumbs (I try to stay away from most grains, except rice, but I'm afrain DH wouldn't like it then!

  4. Perfect. Just saw this recipe and I had bought ground beef thinking of meat loaf. I love meat loaf, and have many recipes that I like, but always in the market for something new from you. Love horseradish and carmelized onions… all together? fantastic. Only have 0 % greek yogurt, no sour cream, but I bet it will be great. thanks once more!

  5. Kann, so glad you enjoyed it, and good to know that flax seed meal was good in this meatloaf too.

  6. My first attempt at meat loaf and it was absolutely wonderful. I used flaxseed meal as recommended in your other meatloaf recipe and it worked out great, no one noticed there were no breadcrumbs! Horseradish gave the meat the kick that it needed, wonderfful! Can't wait to try your other recipes.

  7. Now this is to die for recipe, gonna make it this weekend 🙂

  8. Mike, hope you enjoy it!

  9. Oh my god, this looks outstanding. I can imagine it being my new favorite meatloaf. Great recipe!

  10. Onions aren't restricted on phase one so I don't think the way they're cooked would matter.

  11. I can't wait to make this! I know that caramelizing onions releases the sugar in them so does that make them have more carbs and calories or is it negligible?

  12. I do love a good meatloaf and bacon will make it even better! Yours looks delicious.