Horseradish Meatloaf (with Sour Cream-Horseradish Sauce)

Horseradish Meatloaf is perfect to make on the weekend and enjoy leftovers during the week, and this recipe makes a delicious dinner. If you like meatloaf and enjoy the tasty horseradish sauce that’s served with Corned Beef, I bet you’re going to love this meatloaf that’s seasoned with horseradish!

PIN the Horseradish Meatloaf recipe to try it later!

I think Horseradish Meatloaf is really special in the huge collection of meatloaf recipes in the world! This meatloaf has added flavor from caramelized onions, garlic, horseradish, Worcestershire sauce, and sour cream mixed into the meat! When it’s done, this meatloaf is served with a tasty sauce of sour cream, mayo, and horseradish. And if you use Flaxseed Meal to bind the meatloaf together, this tasty meatloaf is very low in carbs and gluten-free!

But Horseradish Meatloaf is not a quick and easy meatloaf recipe. This is meatloaf to make on Sunday afternoon when you have time to gently caramelize the onions. Then mix the ingredients together, bake it, and mix the sauce. You can have tasty horseradish meatloaf for dinner and enjoy leftovers for lunch all week.

I’m a huge horseradish fan, so I love this recipe! If you’re a fan of spicy horseradish like I am, I hope you’ll think it’s worth the effort for this meatloaf recipe that’s so, so delicious!

What ingredients do you need for this recipe?

(This is only a list of ingredients; please scroll down for complete printable recipe. Or if you use the JUMP TO RECIPE link at the top of the page, it will take you directly to the complete recipe.)

• onions
• olive oil
• Minced Garlic (affiliate link)
• Dried Thyme (affiliate link)
• eggs
• sour cream
• cream-style Prepared Horseradish (affiliate link)
• Worcestershire sauce or Gluten-Free Worcestershire Sauce (affiliate link)
• ground beef
• Flaxseed Meal (affiliate link)
• salt and fresh ground black pepper
• mayo

What is horseradish?

Horseradish is a plant from the same family as mustard, wasabi, broccoli, cabbage, and radishes. It’s a spicy root vegetable that’s used all over the world as a condiment.

Want an Easier Meatloaf Recipe?

If you’re not up for this much work for meatloaf, you may want to make what my sister Pam dubbed Kalyn’s Best Meatloaf, a version I made for years with canned mushroom soup and onion soup mix. That was a very good meatloaf too, back in the day when I used to cook with those kinds of ingredients. But if you have more time, this Horseradish Meatloaf really is amazing for people who enjoy horseradish!

How low in carbs is the Horseradish Meatloaf recipe?

This delicious meatloaf has only 4 net carbs per serving with 34 grams of protein!

How did I make Horseradish Meatloaf lower in carbs?

I originally made this tasty meatloaf with a small amount of breadcrumbs, so it wasn’t gluten-free and did have some carbs. But through the years I’ve started to love Flaxseed Meal (affiliate link) as a binder in meatloaf and meatballs. And the flax seeds have so much fiber that the net carbs are really low. I’ve switched out this recipe to be low-carb, but you can take your choice on using flaxseed meal for lower-carb and gluten-free meatloaf, or make the original version with the same amount of breadcrumbs if you prefer.

How to make Horseradish Meatloaf:

(This is only a summary of the steps for the recipe; please scroll down for complete printable recipe. Or if you use the JUMP TO RECIPE link at the top of the page, it will take you directly to the complete recipe.)

1. Dice two medium onions into fairly small pieces, then heat olive oil and start to cook the onions.
2. Let onions cook at low heat stirring every few minutes until onions are nicely browned and caramelized, about 30 minutes.
3. Don’t rush the browning step and be sure onions don’t burn or they will be bitter.
4. While onions cook, start preheating oven to 375F/190C.
5. When onions are brown, add minced garlic and dried thyme and cook about 2 minutes more.
6. Mix together eggs, sour cream, Prepared Horseradish (affiliate link), and Worcestershire sauce.
7. Put ground beef into a bowl and let it come to room temperature. When onions are done, add Flaxseed Meal (affiliate link) and onion-garlic mixture to the meat and season with salt and fresh ground black pepper.
8. Add egg/sour cream/horseradish/Worcestershire sauce mixture to meat.
9. Use your hands to gently combine until all the ingredients are well-mixed.
10. I bought this broiler pan at a thrift store, and love using it to cook meatloaf. The fat drips down into the lower pan.
11. Form the meat mixture into a loaf and place on top of the broiler pan (or roasting pan of your choice.) I like to make criss-cross slits on top of the meatloaf, but it’s optional!
12. Bake the Horseradish Meatloaf for about 75 minutes, or until meat reaches 160F/55C on an  Instant Read Meat Thermometer (affiliate link).
13. Let meatloaf cool for 10-15 minutes before cutting; then serve with Sour Cream-Horseradish Sauce if desired.

Make It a Low-Carb Meal:

>Horseradish Meatloaf with Sour Cream Horseradish Sauce would be great served with one of these side dishes:

• Pureed Cauliflower with Garlic, Parmesan, and Goat Cheese
• Kale and Red Cabbage Slaw
• Stir-Fried Spinach with Garlic and Parmesan
• Instant Pot Green Beans
• Green Bean Tomato Feta Salad

More Tasty Meatloaf or Meatballs:

• Bacon Cheeseburger Meatballs
• Beef and Sausage Italian Meatloaf
• Baked Swedish Meatballs

Continue to Content

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4.6 Stars (9 Reviews)

Yield: 8 servings

Horseradish Meatloaf (with Sour Cream-Horseradish Sauce)

Prep Time 1 hour

Cook Time 1 hour 15 minutes

Total Time 2 hours 15 minutes

Make this Horseradish Meatloaf (with Sour Cream-Horseradish Sauce) on the weekend and enjoy leftovers during the week!

Ingredients

Ingredients

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• 2 medium onions, diced into small pieces
• 1 T tsp. olive oil (more or less, depending on your pan)
• 1 T finely minced garlic
• 1 tsp. dried thyme
• 2 eggs, beaten
• 1/4 cup sour cream
• 3 T cream-style horseradish (not horseradish sauce)
• 1 T Worcestershire sauce
• 2 lbs. ground beef
• 1/2 cup Flaxseed Meal (see notes)
• salt and fresh ground black pepper to taste

Sauce Ingredients

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• 1/4 cup sour cream
• 2 T mayo
• 2 T cream-style horseradish

Instructions

1. Dice two medium onions into fairly small pieces, then heat olive oil in a large heavy pan and start to cook the onions over low heat.
2. Let onions cook at low heat stirring every few minutes until onions are nicely browned and caramelized, about 30 minutes.
3. Don’t rush this step and be sure onions don’t burn or they will be bitter.
4. While onions cook, start preheating oven to 375F/190C.
5. When onions are done, add minced garlic and dried thyme and cook about 2 minutes more.
6. Mix together eggs, sour cream, horseradish, and Worcestershire sauce.
7. Put ground beef into a bowl and let it come to room temperature.
8. Add Flaxseed Meal (affiliate link) and onion-garlic mixture to the meat and season with salt and fresh ground black pepper.
9. Then add egg/sour cream/horseradish/Worcestershire sauce mixture to meat. (Adding this on top of the onions will help cool them.)
10. Use your hands to gently combine until all the ingredients are well-mixed.
11. Form the meat mixture into a loaf and place on top of the broiler pan (or roasting pan of your choice.)
12. I like to make criss-cross slits on top of the meatloaf, but it's completely optional!
13. Bake meatloaf for about 75 minutes, or until meat reaches 55-160F on an  Instant Read Meat Thermometer (affiliate link).
14. Let meatloaf cool for 10-15 minutes before cutting.
15. Then stir together sauce ingredients and serve the Horseradish Meatloaf hot, with Sour Cream-Horseradish Sauce if desired.

Notes

I loved this with Flaxseed Meal (affiliate link) for a low-carb version, but make it with breadcrumbs if you prefer.

Recipe adapted by Kalyn from notes copied years ago from a friend’s cookbook, but unfortunately the notes didn’t include the name of the cookbook.

Nutrition Information

Yield

8

Serving Size

1
Amount Per Serving Calories 475Total Fat 34gSaturated Fat 12gTrans Fat 1gUnsaturated Fat 18gCholesterol 168mgSodium 252mgCarbohydrates 6gFiber 2gSugar 2gProtein 34g

Nutrition information is automatically calculated by the Recipe Plug-In I am using. I am not a nutritionist and cannot guarantee 100% accuracy, since many variables affect those calculations.

Did you make this recipe?

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Low-Carb Diet / Low-Glycemic Diet / South Beach Diet Suggestions:
When made with Flaxseed Meal (affiliate link), this Horseradish Meatloaf is a low-carb recipe, suitable for low-carb and Keto eating plans. When it’s made with ground beef with 10% fat or less, the meatloaf will be approved for any phase of the original South Beach Diet. The Sour Cream Horseradish Sauce is a bit high in fat for South Beach if you use full-fat ingredients, but you’re not going to eat much of it.

Find More Recipes Like This One:
Use Oven Dinners to find more recipes like this one. Use the Diet Type Index to find recipes suitable for a specific eating plan. You might also like to follow Kalyn’s Kitchen on Pinterest, on Facebook, on Instagram, on TikTok, or on YouTube to see all the good recipes I’m sharing there.

Historical Notes for this Recipe:
This recipe for tasty meatloaf flavored with horseradish was first posted in 2010. It was last updated with more information and the option to use flaxseed meal to make it a low-carb meatloaf in 2021. The recipe was last updated with more information in 2026.