Chicken Alfredo Lasagna Casserole

Chicken Alfredo Lasagna is a delicious and easy mock lasagna casserole to make with chicken, but try this with leftover turkey too! And this tasty lasagna casserole makes great leftovers to reheat later!

PIN Chicken Alfredo Lasagna Casserole to try it later!

This recipe for Chicken Alfredo Lasagna Casserole is a sibling of another casserole that’s been super popular. And this new lasagna casserole recipe also uses Folios Parmesan Cheese Wraps for the noodle layer.

I’m still finding Folios at my Costco and you can get them at Amazon if you don’t find them in your store. And Kara and I both loved this when we tested the recipe, and we also thought the leftovers reheated well, making this a perfect Weekend Food Prep recipe!

I used low-carb Alfredo sauce in a jar to make the Chicken Alfredo Lasagna extra easy to get into the oven. And the other shortcut was using one of those packages of Costco Rotisserie Chicken breast for the chicken. Have you tried that amazing product?

But this Chicken Alfredo Lasagna would also be amazing to make with with leftover turkey when you’re lucky enough to get some! If you like the idea of a layered casserole with chicken and Alfredo sauce, I hope you will give it a try!

What ingredients do you need?

(This is only a list of ingredients; please scroll down for complete printable recipe. Or if you use the JUMP TO RECIPE link at the top of the page, it will take you directly to the complete recipe.)

• mushrooms
• Olive Oil (affiliate link)
• chicken
• onion
• Poultry Seasoning (affiliate link)
• Garlic Powder (affiliate link)
• Dried Sage (affiliate link)
• Rao’s Alfredo Sauce (affiliate link)
• Parmesan Folios Cheese Wraps (affiliate link)
• Mozzarella cheese

Why I love Rao’s Alfredo Sauce for this Chicken Alfredo Lasagna:

I’m recommending Rao’s Alfredo Sauce (affiliate link) for this recipe because the flavor of the Rao’s Alfredo is so, so good. But this sauce is pricey and also can be hard to find! Most bottled Alfredo sauce is low in carbs, so if you like another brand of low-carb Alfredo Sauce, you can definitely use that. Or if you want to make your own low-carb sauce you could try Creamy Low-Carb Alfredo Sauce or Creamy Cauliflower Sauce.

Do you need Folios Parmesan Cheese Wraps for Chicken Alfredo Lasagna?

If you can’t find Folios Parmesan Cheese Wraps at your store, please don’t let that stop you from making this tasty mock lasagna! You can buy the Parmesan Folios Cheese Wraps (affiliate link) at Amazon.com, or just use a firm sliced cheese like Provolone to replace the Folios. That cheese will probably melt a bit more but it’s still going to be delicious.

How low in carbs is the Chicken Alfredo Lasagna?

This tasty casserole with chicken and Alfredo sauce only has about 6.5 net carbs per serving with 47 grams of protein!

Want more low-carb lasagna or lasagna casserole recipes?

Check out Best Keto Lasagna Recipes for more tasty recipes for lasagna and mock lasagna casserole!

More Recipes for fans of Rao’s:

If you’re a fellow lover of Rao’s low-carb sauces you can check out 20 Recipes with Rao’s Pasta and Pizza Sauce for more recipe ideas.

How to Make Chicken Alfredo Lasagna Casserole:

(This is only a summary of the steps for the recipe; please scroll down for complete printable recipe. Or if you use the JUMP TO RECIPE link at the top of the page, it will take you directly to the complete recipe.)

1. This first photo shows the pack of rotisserie chicken breast from Costco that we used for the chicken. 
2. You need 8 cups of diced chicken (or turkey) shown here in a giant measuring cup, but if you get the Costco package you can use the whole package if you don’t mind the chicken/mushroom layer being slightly thicker.
3. Chop up 1 lb. mushrooms, heat olive oil, and cook mushrooms until nicely browned. Remove mushrooms to a plate.
4. Add chopped onion and cook about 3 minutes.
5. Then add Poultry Seasoning, Garlic Powder, and Dried Sage and cook a minute or two longer.
6. Add the mushrooms and diced chicken to the frying pan and gently stir to combine.
7. Then add Rao’s Alfredo Sauce (affiliate link) or your favorite Alfredo, stir to combine, and cook at a low simmer about 10 minutes.
8. Spray the baking dish with non-stick spray.
9. Cut the Folios in half and cover the bottom of the dish, putting the straight side along the edge of the dish. 
10. Put half the chicken/mushroom mixture over the Folios.
11. Put 1 1/2 cups grated Mozzarella over the chicken/mushroom layer. 
12. Make another layer of Folios, chicken/mushroom mixture, and the other 1 1/2 cups grated Mozzarella. (You can get by with a bit less cheese if you prefer.)
13. Bake at 375F/190C for 30-35 minutes, or until the mixture is hot and the top is browned.
14. Let it sit for 10 minutes before you cut into eight pieces to serve.
15. Chicken Alfredo Lasagna freezes well and can be reheated in the microwave.

Make it a Low-Carb Meal:

This tasty lasagna casserole would taste great with any of these side dishes:

• Caesar Salad with Kale, Romaine, and Shaved Parmesan
• Kalyn’s Favorite Baby Arugula Salad
• Mary’s Easy Spring Mix Salad
• Lemon Parmesan Kale Salad
• Ottolenghi’s Perfect Lettuce Salad

More Low-Carb Casseroles using Leftover Chicken or Turkey:

• Low-Carb Turkey Casserole
• Cheesy Chicken Broccoli Curry Casserole
• Turkey Shepherd’s Pie with Cauliflower Topping

Continue to Content

Print

4.7 Stars (23 Reviews)

Yield: 8 servings

Chicken Alfredo Lasagna Casserole

Prep Time 20 minutes

Cook Time 30 minutes

Additional Time 10 minutes

Total Time 1 hour

This Chicken Alfredo Lasagna Casserole is a delicious way to use chicken, but don't forget about this recipe when you need ideas for leftover turkey! And this lasagna casserole recipe uses several convenience products that make it extra-easy to get on the table.

Ingredients

Toggle ingredient group

• 1 lb. mushrooms, chopped into medium-size pieces
• 1 T + 2 tsp. olive oil
• 8 cups diced, cooked chicken (see notes)
• 1 small onion, chopped
• 2 tsp. Poultry Seasoning
• 2 tsp. garlic powder
• 1 tsp. dried sage (sometimes called rubbed sage; more or less to taste)
• one 15 oz. jar Rao's Alfredo Sauce
• 4 Parmesan Cheese Folios, cut in half
• 3 cups grated Mozzarella cheese

Instructions

1. Cut up about 8 cups of diced chicken, a bit more or less won't hurt.
2. Chop up 1 lb. mushrooms, heat the 1 T olive oil in a large frying pan, and cook until mushrooms are nicely browned and any released liquid had evaporated. Remove mushrooms to a plate.
3. Add chopped onion (and a little more oil if needed) and cook the onion about 3 minutes.
4. Then add Poultry Seasoning (affiliate link), Garlic Powder (affiliate link), and Dried Sage (affiliate link) and cook a minute or two longer.
5. Add the mushrooms and diced chicken to the frying pan and gently stir to combine.
6. Then add  Rao's Alfredo Sauce (affiliate link) or your favorite Alfredo Sauce, stir to combine, and cook at a low simmer about 10 minutes, or until the sauce has thickened and reduced a bit.
7. I used my favorite lasagna dish that's 7.5" x 11.5" x 3 inches deep; choose a size that's close to that. Spray the baking dish with non-stick spray.
8. Cut the Folios in half and cover the bottom of the dish, putting the straight edge along the side of the dish. (I only needed two Folios per layer for my size dish but bigger casserole dishes might need three.)
9. Put half the chicken/mushroom mixture over the Folios, spreading out so it's an even thickness.
10. Put 1 1/2 cups grated Mozzarella over the chicken/mushroom layer.
11. Make another layer of Folios, chicken/mushroom mixture, and the other 1 1/2 cups grated Mozzarella. (You can get by with a bit less cheese if you prefer.)
12. Bake at 375F/190C for 30-35 minutes, or until the mixture is bubbling hot and the top is lightly browned.
13. Let Chicken Alfredo Lasagna sit for 10 minutes or so before you cut into eight pieces. (It will still taste great if you can't wait that long, it just won't hold together as well.)

Notes

You can use a bit more or less chicken, depending on what you have.

Use leftover turkey if you have that!

Use any low-carb Alfredo Sauce you have if you don't have Rao's.

This freezes very well and reheats beautifully in the microwave.

This recipe created by Kalyn and Kara and inspired by Folios Parmesan Cheese Wraps that I found at Costco!

Nutrition Information

Yield

8

Serving Size

1
Amount Per Serving Calories 554Total Fat 35gSaturated Fat 17gUnsaturated Fat 18.4gCholesterol 212mgSodium 816mgCarbohydrates 8gFiber 1.5gSugar 3.1gProtein 47g

Nutrition information is automatically calculated by the Recipe Plug-In I am using. I am not a nutritionist and cannot guarantee 100% accuracy, since many variables affect those calculations.

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Low-Carb Diet / Low-Glycemic Diet / South Beach Diet Suggestions:
Chicken Alfredo Lasagna is a great dish for low-carb diet plans, including Keto. The Parmesan Cheese wraps are probably a bit high in fat, but personally I’d eat this for any phase of the original South Beach Diet, Sse low-carb tortillas for that layer if you prefer. South Beach would recommend lower-fat Alfredo Sauce and reduced fat cheese for this recipe if you’re following the letter of the law.

Find More Recipes Like This One:
Use Casserole Recipes to find more low-carb casseroles like this one! Use the Diet Type Index to find recipes suitable for a specific eating plan. You might also like to follow Kalyn’s Kitchen on Pinterest, on Facebook, on Instagram, on TikTok, or on YouTube to see all the good recipes I’m sharing there.

Historical Notes for this Recipe:
This low-carb lasagna casserole recipe with Folio’s Parmesan Cheese wraps, chicken, and Alfredo sauce was posted in 2020. It was last updated with more information in 2026.